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Modulation der durch Artesunat induzierten östrogenen Wirkungen

Modulation der durch Artesunat induzierten östrogenen Wirkungen

Evana Figueiredo J. de Souza

55,04 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2023
Materia
Farmacología
ISBN:
9786206440369
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Artesunat ist ein von Artemisinin abgeleitetes Medikament, das zur Behandlung der aggressivsten Form von Malaria eingesetzt wird. Aufgrund seiner toxischen Wirkung auf den Fortpflanzungstrakt des Embryos wird seine Anwendung im ersten Trimester der Schwangerschaft jedoch nicht empfohlen. Diese Reproduktionstoxizität könnte mit der östrogenen Wirkung dieses Arzneimittels zusammenhängen. Trotz der Hinweise auf die östrogene Wirkung von Artesunat wurden bisher keine Studien zu diesem Thema durchgeführt. Und genau das wird in diesem Buch näher beleuchtet.

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    Artesunate is a drug derived from artemisinin used to treat the most aggressive form of malaria. However, its use is not recommended in the first trimester of pregnancy due to its toxic effects on the embryo’s reproductive tract. This reproductive toxicity may be related to the oestrogenic action of this drug. Despite the evidence of artesunate’s oestrogenic action, no studies ...
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